• 59°

Dr. Chris Magryta: Vaccine response

By Dr. Chris Magryta
Salisbury Pediatric Associates

It has long been known that metabolic health corresponds to vaccine effectiveness as well as general immunity against disease. Elderly individuals fair poorly in both categories as aging is often associated with increased metabolic disease, decrease immune activation and antibody production. Most of these issues are related to lifestyle dietary choices as COVID-19 has laid bare.

Children are much better at developing immune responses, however,

This can be compromised by poor metabolic status, prematurity and being younger than 6 months of age. This is believed to be primarily driven by pregnancy and post-partum maternal nutritional health in this first half year of a child’s life. Therefore, it is critical that we address these issues with nursing mothers and their babes. (Obanewa et. al. 2017)

Looking at the literature, that is reasonable for developing countries, but nonexistent for the developed world, we can settle on a few things. Neonatal iron status is important, gut health is important, breast feeding is a massive plus and micronutrient balance appears to be important in general.

In a recent study by Stoffel and colleagues in the Journal Frontiers in Immunology, we see a report of weaker antibody responses to vaccination in children with low iron stores. (Stoffel et. al. 2020) In a study by Dr. Okala published in PlosMedicine in 2019, her group had this to say, “According to our results from rural Gambia, maternal supplementation with MMN combined with PE during pregnancy enhanced antibody responses to the DTP vaccine in early infancy. Provision of nutritional supplements to pregnant women in food insecure settings may improve infant immune development and responses to EPI vaccines.” (Okala et. al. 2019)

Without any data to guide us in the United States, what should we do? I fall back on the simplest of rules, what were we supposed to do? What was mom supposed to do?

In a country replete with financial governmental ability, we should absolutely provide women and children with adequate nourishment, promote breastfeeding, supplement with prenatal vitamins and vaccinate to prevent the meaningless loss of life to preventable diseases.

We should and must encourage mothers to eat healthy, avoid toxins, breastfeed, take their prenatal vitamins and exercise. Then, it is my belief that the immune system of mom and child will be the most prepared for any insult moving forward. And, oh by the way, the interventions are safe and reasonable.

Dr. Chris Magryta is a physician at Salisbury Pediatric Associates. Email him at newsletter@salisburypediatrics.com .

About Post Lifestyles

Visit us on Facebook: https://www.facebook.com/SalPostLifestyle/ and Twitter @postlifestlyes for more content

email author More by Post

Comments

Elections

Requests for absentee ballots top 9,000 in Rowan

Local

Spencer approves supplemental USDA loan for Park Plaza project

Business

11 locals will make up Empire Redevelopment Task Force

Local

New finance director excited to prove himself, continue on path set by predecessor

Coronavirus

County health officials report four new COVID-19 deaths

Elections

Trump promotes health care ‘vision’ at stop in Charlotte but gaps remain

Crime

Blotter: Woman charged with stealing mom’s dog

Business

Rowan County hires Howden as new finance director

Local

Exhibit about Jim Crow-era travel on display at NC Transportation Museum

Elections

GOP elections board members resign over absentee settlement

Crime

Drive-by shooting injures 24-year-old Salisbury man

Crime

Highway Patrol: Vehicle fled after striking, killing pedestrian on Camp Road

Local

Locals to be inducted into NC Military Veterans Hall of Fame

Business

Fall fun, with a twist: Patterson Farm adjusts to guidelines, offers new version of traditional events

Nation/World

Sayers, Piccolo friendship lives on in ‘Brian’s Song’

Education

Partners in learning passes last year’s special needs fashion show fundraiser with all-virtual event

Education

Shoutouts

Elections

Former history teacher to use ‘working knowledge of the issues’ in state House race

Business

Chamber adds more than 50 new businesses during Total Resource Campaign

Education

School board candidates for Salisbury seat split on consolidation

Education

Virtually no internet: Rural NC families struggle with online access for school-age children

Education

Horizons Unlimited taking learning to students this semester

Nation/World

NTSB: Pilot’s actions likely caused Earnhardt Jr. plane crash

Nation/World

2 Louisville officers shot amid Breonna Taylor protests